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NSAID in CKD — GPhC CRA MCQ

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EasyRenal and Hepatic ImpairmentNSAID in CKDGPhC CRA

A man with CKD stage 4 and hypertension asks for naproxen for a sports injury. He takes losartan. What is the most appropriate action?

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Correct answer: C — Avoid oral naproxen and refer if pain is severe or persistent

NSAIDs can worsen renal function and increase hyperkalaemia risk, especially with ACE inhibitors or ARBs and advanced CKD. Safer analgesic options and clinical review should be considered. Medication changes should be made by the prescriber.

Reference: BNF; NICE CKS