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Thiazide and gout — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsThiazide and goutGPhC CRA

A 59-year-old man with recurrent gout has been prescribed indapamide MR for hypertension. He is worried because his last gout flare was two weeks ago. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DDiscuss a calcium-channel blocker or ACE inhibitor with the prescriber

Thiazide-like diuretics can increase urate and may worsen gout. Alternative antihypertensives may be preferable depending on patient factors. The pharmacist should discuss the concern with the prescriber rather than initiating prescription-only changes.

Reference: BNF; NICE CKS