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Clozapine myocarditis — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyClozapine myocarditisGPhC CRA

A patient started clozapine three weeks ago and reports chest pain, breathlessness and flu-like symptoms. What is the most appropriate action?

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Correct answer: E — Refer urgently for assessment of possible clozapine myocarditis

Clozapine can rarely cause myocarditis, particularly early in treatment. Chest pain, breathlessness and flu-like symptoms require urgent assessment. The clozapine monitoring service and prescriber should be involved.

Reference: BNF