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Paracetamol liver disease — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentParacetamol liver diseaseGPhC CRA

A patient with decompensated cirrhosis asks to buy co-codamol for back pain. He has been drinking heavily again. What is the most appropriate action?

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Correct answer: C — Refer for clinical advice before supply because hepatic risk and opioid risks are present

Advanced liver disease and ongoing alcohol use increase the need for careful analgesic selection and dosing. Co-codamol also adds opioid-related sedation and constipation risk. Referral for individualised clinical advice is safest.

Reference: BNF; NICE CKS