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NSAID gastroprotection — GPhC CRA MCQ

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ModerateGastro-intestinal TherapeuticsNSAID gastroprotectionGPhC CRA

A 73-year-old woman with osteoarthritis is prescribed naproxen 500 mg twice daily. She has previous peptic ulcer disease and takes sertraline. What is the most appropriate alternative?

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Correct answer: E — Query gastroprotection and bleeding risk before supply

NSAIDs increase gastrointestinal bleeding risk, especially in older people and those with previous ulcer disease. Sertraline may add bleeding risk. Gastroprotection and the need for NSAID therapy should be reviewed.

Reference: BNF; NICE CKS