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Thyroid and warfarin — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsThyroid and warfarinGPhC CRA

A patient established on warfarin starts levothyroxine for hypothyroidism. The anticoagulation clinic asks the pharmacy to reinforce advice. What monitoring is required?

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Correct answer: A — Closer INR monitoring during thyroid correction

Changes in thyroid status can alter warfarin sensitivity. As hypothyroidism is corrected, anticoagulant response may change, so closer INR monitoring is appropriate. The anticoagulation clinic should guide dose adjustment.

Reference: BNF