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ACE inhibitor cough — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsACE inhibitor coughGPhC CRA

A 58-year-old woman taking lisinopril for hypertension has developed a persistent dry cough since starting treatment. She has no fever, wheeze or reflux symptoms. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Discuss switching to an angiotensin-II receptor blocker

A persistent dry cough is a recognised class effect of ACE inhibitors. Switching to an angiotensin-II receptor blocker is a common alternative when the cough is troublesome. Changing to another ACE inhibitor may not resolve the issue.

Reference: BNF; NICE CKS