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Methotrexate weekly dosing — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsMethotrexate weekly dosingGPhC CRA

A patient collects methotrexate 2.5 mg tablets for rheumatoid arthritis. The prescription says 15 mg once weekly on Mondays. The patient thinks tablets are usually daily. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Take six tablets once weekly on the stated day and seek help if dosing is unclear

Methotrexate for rheumatoid arthritis is taken once weekly; daily dosing errors can be fatal. The pharmacist should confirm the dose and day, reinforce warning symptoms, and ensure folic acid arrangements are clear. Ambiguity should be resolved before supply.

Reference: BNF; MEP