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Heparin-induced thrombocytopenia — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyHeparin-induced thrombocytopeniaGPhC CRA

A patient discharged on dalteparin after surgery phones with a painful swollen leg and a hospital message saying her platelet count has fallen. What is the most appropriate action?

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Correct answer: ARefer urgently because thrombosis with falling platelets suggests possible HIT

Heparin-induced thrombocytopenia can paradoxically cause thrombosis with a fall in platelets. A painful swollen leg may indicate DVT and needs urgent assessment. The patient should not self-adjust anticoagulant dosing.

Reference: BNF