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Rifampicin and contraception — GPhC CRA MCQ

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ModerateDrug InteractionsRifampicin and contraceptionGPhC CRA

A woman taking a combined oral contraceptive is prescribed rifampicin for suspected TB exposure. She asks whether her usual pill is enough. What is the most important interaction to flag?

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Correct answer: E — Rifampicin can reduce hormonal contraceptive effectiveness

Rifampicin is a potent enzyme inducer and can reduce effectiveness of hormonal contraception. Alternative or additional contraception is needed, with advice tailored to the method and duration. Emergency contraception advice may also be relevant.

Reference: BNF; FSRH guidance