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Digoxin and verapamil — GPhC CRA MCQ

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HardDrug InteractionsDigoxin and verapamilGPhC CRA

A patient taking digoxin for AF is prescribed verapamil MR for rate control. He reports nausea and his pulse is 48 bpm. What is the most important interaction to flag?

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Correct answer: B — Verapamil can increase digoxin levels and bradycardia risk

Verapamil can increase digoxin concentrations and both drugs can slow AV nodal conduction. Nausea and bradycardia are concerning for toxicity or excessive rate control. The prescription should be reviewed urgently.

Reference: BNF