skip to main content

Donepezil bradycardia — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCNS TherapeuticsDonepezil bradycardiaGPhC CRA

An 80-year-old man taking donepezil presents a new prescription for bisoprolol. His carer reports recent dizzy spells and his pulse is 52 bpm. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Query the prescription because bradycardia risk is increased

Donepezil can cause bradycardia and syncope, and beta-blockers can compound this. A low pulse and dizziness make the new prescription clinically concerning. The prescriber should review before supply.

Reference: BNF