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Mesalazine monitoring — GPhC CRA MCQ

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HardGastro-intestinal TherapeuticsMesalazine monitoringGPhC CRA

A patient is starting oral mesalazine for ulcerative colitis. Which safety-monitoring plan should be confirmed before the first supply?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Baseline renal function followed by periodic renal monitoring

Mesalazine can rarely cause renal injury, including interstitial nephritis. Renal function should be assessed before treatment and monitored during therapy at an interval based on product information, renal risk and the local shared-care arrangement.

Reference: BNF: mesalazine: https://bnf.nice.org.uk/drugs/mesalazine/