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PPI step-down — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsPPI step-downGPhC CRA

A man has taken omeprazole for uncomplicated reflux for several months and symptoms are controlled. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Discuss step-down to the lowest effective dose or intermittent use, with referral if alarm symptoms occur

Long-term PPI therapy should be reviewed and reduced where clinically appropriate. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: NICE CKS; BNF