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Sertraline early nausea — GPhC CRA MCQ

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HardCNS TherapeuticsSertraline early nauseaGPhC CRA

A woman started sertraline five days ago and has nausea and mild headache but no suicidal thoughts. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Continue if tolerable because early gastrointestinal adverse effects often improve and seek help if mood worsens

Early SSRI adverse effects are common but safety-netting is essential. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; NICE CKS