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Mesalazine renal monitoring — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsMesalazine renal monitoringGPhC CRA

A patient with ulcerative colitis starts oral mesalazine and the GP asks what safety monitoring is relevant. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Check renal function before treatment and periodically during treatment

Mesalazine can rarely cause renal impairment including interstitial nephritis. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF