Missed methadone instalments — GPhC CRA MCQ
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Correct answer: C — Follow the instalment wording and local SOP, and contact the prescriber if clinical safety is uncertain
Missed opioid substitution doses can reduce tolerance and make accumulated dosing dangerous. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.
Reference: MEP; Misuse of Drugs Regulations 2001