Lamotrigine combined pill — GPhC CRA MCQ
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Correct answer: A — Combined hormonal contraception can lower lamotrigine concentrations and affect seizure control
Oestrogen-containing contraception can increase lamotrigine clearance. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.
Reference: BNF