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SSRI hyponatraemia — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetySSRI hyponatraemiaGPhC CRA

An older woman started citalopram two weeks ago and now has confusion, headache and unsteadiness while taking a thiazide. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Refer for assessment including serum sodium because SSRI-associated hyponatraemia is possible

SSRIs can cause hyponatraemia, especially in older adults and with diuretics. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; NICE CKS