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Nitrofurantoin renal function — GPhC CRA MCQ

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ModerateInfectionsNitrofurantoin renal functionGPhC CRA

An older woman with lower urinary tract infection has a nitrofurantoin prescription and eGFR 28 mL/minute/1.73 m2. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DQuery the prescription because nitrofurantoin may be unsuitable at this renal function

Nitrofurantoin needs adequate renal function for urinary efficacy and safety. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; NICE CKS