Methotrexate large quantity — GPhC CRA MCQ
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Correct answer: D — Query the unusually large quantity before dispensing
Methotrexate is high risk and unusually large quantities increase harm from dosing errors. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.
Reference: BNF; MEP