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Nitrofurantoin hepatic reaction — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentNitrofurantoin hepatic reactionGPhC CRA

A patient with previous nitrofurantoin-induced hepatitis presents another nitrofurantoin prescription. What is the most appropriate action?

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Correct answer: C — Do not supply until the prescriber reviews the previous hepatic reaction

Previous serious hepatic reaction is clinically relevant to re-exposure. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF