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Spironolactone salt substitute — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsSpironolactone salt substituteGPhC CRA

A man with heart failure taking spironolactone and ramipril asks about a potassium-containing salt substitute. What would you advise the patient?

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Correct answer: E — Avoid potassium salt substitutes unless the heart failure team specifically agrees

Spironolactone and ACE inhibitors increase hyperkalaemia risk. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF