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Domperidone cardiac risk — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsDomperidone cardiac riskGPhC CRA

An older woman with arrhythmia taking amiodarone asks to continue domperidone long term. What is the most appropriate action?

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Correct answer: B — Refer to the prescriber because domperidone has cardiac risk and interacting QT-prolonging therapy is present

Domperidone can prolong QT and cardiac risk rises with age, arrhythmia and interacting medicines. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; MHRA