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Colestyramine levothyroxine — GPhC CRA MCQ

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EasyDrug InteractionsColestyramine levothyroxineGPhC CRA

A patient taking levothyroxine starts colestyramine for bile acid diarrhoea. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BColestyramine can bind levothyroxine and reduce absorption

Colestyramine binds medicines in the gut and can reduce absorption. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF