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PPI and recurrent C difficile — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsPPI and recurrent C difficileGPhC CRA

A care home resident with recurrent C. difficile remains on lansoprazole without a current indication. What is the most appropriate action?

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Correct answer: A — Recommend prescriber review of ongoing proton pump inhibitor need

PPI therapy should be reviewed where there is no ongoing indication, particularly with infection risk. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; NICE CKS