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Phenytoin folic acid — GPhC CRA MCQ

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HardDrug InteractionsPhenytoin folic acidGPhC CRA

A patient taking phenytoin is prescribed high-dose folic acid by a specialist. What is the most appropriate action?

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Correct answer: EFolic acid can reduce phenytoin concentrations and seizure control may need monitoring

Folic acid may reduce phenytoin plasma concentration in some patients. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF