skip to main content

Methadone zopiclone alcohol — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

EasyDrug InteractionsMethadone zopiclone alcoholGPhC CRA

A patient on methadone supervised consumption is prescribed zopiclone and drinks alcohol at night. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Methadone with zopiclone and alcohol increases sedation and respiratory depression risk

Opioids, hypnotics and alcohol have additive central nervous system depressant effects. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; MEP