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Sildenafil doxazosin — GPhC CRA MCQ

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ModerateDrug InteractionsSildenafil doxazosinGPhC CRA

A man taking doxazosin has recent postural dizziness and asks for sildenafil. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Sildenafil with doxazosin can increase symptomatic hypotension risk

Both medicines can lower blood pressure, and dizziness suggests susceptibility. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF