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Clozapine infection symptoms — GPhC CRA MCQ

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ModerateCNS TherapeuticsClozapine infection symptomsGPhC CRA

A patient taking clozapine reports fever, sore throat and mouth ulcers when collecting a repeat. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Refer urgently for same-day blood count assessment

Clozapine can cause neutropenia and infection symptoms require urgent assessment. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; clozapine monitoring service guidance