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Valproate pregnancy planning — GPhC CRA MCQ

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HardCNS TherapeuticsValproate pregnancy planningGPhC CRA

A woman taking sodium valproate for epilepsy says she is planning pregnancy and has not seen a specialist recently. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BAdvise urgent specialist review before pregnancy and do not advise abrupt discontinuation

Valproate is highly teratogenic but abrupt cessation can precipitate seizures. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: MHRA; BNF