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ACE inhibitor initiation — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCardiovascular TherapeuticsACE inhibitor initiationGPhC CRA

A 55-year-old with diabetes starts ramipril 2.5 mg daily for hypertension. Baseline renal function is normal and the GP asks about follow-up tests. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Check serum creatinine/eGFR and potassium within 1 to 2 weeks

ACE inhibitors can reduce renal perfusion pressure and increase potassium soon after initiation or titration. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; NICE CKS