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Warfarin NSAID request — GPhC CRA MCQ

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EasyCardiovascular TherapeuticsWarfarin NSAID requestGPhC CRA

A patient taking warfarin after an unstable INR asks to buy ibuprofen for knee pain. There are no signs of active bleeding. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EAvoid ibuprofen and use safer analgesia such as short-term paracetamol with anticoagulation advice if needed

NSAIDs increase gastrointestinal bleeding risk when combined with warfarin. In this scenario, the pharmacist should prioritise safe supply, appropriate counselling and timely referral or clarification where needed. This is the single best answer because the other options would either delay assessment, ignore a clinically significant risk, or create an unsafe legal or professional outcome.

Reference: BNF; MEP