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Montelukast neuropsychiatric reactions — GPhC CRA MCQ

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ModerateRespiratory TherapeuticsMontelukast neuropsychiatric reactionsGPhC CRA

A parent collecting montelukast 5mg chewable tablets for a child with asthma says the child has had new nightmares and mood changes since starting it. What is the most appropriate action?

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Correct answer: E — Contact the prescriber promptly and report possible neuropsychiatric adverse effects

Montelukast is associated with neuropsychiatric reactions including nightmares, mood changes and behavioural symptoms. New symptoms should prompt prescriber review, and suspected adverse reactions may warrant Yellow Card reporting. The pharmacist should not dismiss the concern.

Reference: MHRA Drug Safety Update; BNF