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Macrogol and renal impairment — GPhC CRA MCQ

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EasyRenal and Hepatic ImpairmentMacrogol and renal impairmentGPhC CRA

A patient with chronic kidney disease asks for constipation treatment. He has been told to avoid high-magnesium medicines. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Consider macrogol as an osmotic laxative option if otherwise suitable

Some magnesium-containing laxatives can accumulate in significant renal impairment and should be used with caution or avoided. Macrogol is commonly used for constipation and may be a suitable option depending on the patient. Severe constipation, obstruction symptoms or fluid restrictions require clinical advice. Product selection should consider renal status and comorbidities.

Reference: BNF; NICE CKS