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Calcium and bisphosphonate — GPhC CRA MCQ

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EasyDrug InteractionsCalcium and bisphosphonateGPhC CRA

A patient taking weekly alendronic acid also takes calcium carbonate each morning. She asks whether both can be taken together to reduce tablet burden. What is the most important interaction to flag?

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Correct answer: B — Calcium reduces alendronic acid absorption if taken at the same time

Calcium salts reduce absorption of alendronic acid. Alendronic acid should be taken with plain water on waking, before food, drinks or other medicines, and the patient should remain upright. Calcium can be taken later according to product instructions. Correct timing is central to efficacy.

Reference: BNF; NICE CKS