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Pancreatic enzyme replacement — GPhC CRA MCQ

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ModerateGI TherapeuticsPancreatic enzyme replacementGPhC CRA

A patient prescribed pancreatin capsules for pancreatic insufficiency says she takes the full daily dose at bedtime because she forgets during the day. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Take pancreatin with meals and snacks so enzymes mix with food

Pancreatin should be taken with meals and snacks because it works by aiding digestion of food. Taking the full daily amount at bedtime will not match enzyme delivery to food intake. Enteric-coated preparations should not be crushed or mixed with hot liquids. Pale, bulky stool may indicate inadequate enzyme replacement and needs review.

Reference: BNF; NICE CKS