skip to main content

Topiramate and contraception — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardDrug InteractionsTopiramate and contraceptionGPhC CRA

A woman taking topiramate for migraine prevention asks for advice after starting a combined oral contraceptive. She is of childbearing potential. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Contraceptive efficacy and pregnancy-prevention requirements need review

Topiramate has teratogenic risk and is subject to pregnancy-prevention considerations. It can also affect hormonal contraception at some doses, so contraception should be reviewed carefully. The patient should be referred to the prescriber or specialist service for individualised advice. A combined pill does not remove medicine-related pregnancy risk.

Reference: BNF; FSRH; MHRA