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ACE inhibitor and potassium salt substitute — GPhC CRA MCQ

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EasyDrug InteractionsACE inhibitor and potassium salt substituteGPhC CRA

A patient taking lisinopril asks whether a potassium-based salt substitute is a good option for his low-salt diet. What is the most important interaction to flag?

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Correct answer: E — Increased risk of hyperkalaemia

ACE inhibitors can increase serum potassium. Potassium-containing salt substitutes can add to this effect and increase the risk of hyperkalaemia. Patients should be advised not to use such products without clinician advice, especially if renal impairment or potassium-sparing medicines are present. Dietary sodium reduction can be achieved in safer ways.

Reference: BNF; NICE CKS