skip to main content

Sick day metformin — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

EasyEndocrine TherapeuticsSick day metforminGPhC CRA

A patient taking metformin has diarrhoea and has been unable to keep fluids down since yesterday. He asks whether to continue taking it. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Temporarily stop metformin during dehydration and seek medical advice if symptoms persist

Metformin may need to be withheld during acute dehydration because renal function can deteriorate and lactic acidosis risk may increase. Patients should be advised on sick-day guidance and when to seek medical attention. Restarting is usually considered once eating and drinking normally and renal function is stable if needed. Dose doubling is not appropriate.

Reference: NICE CKS; BNF