Heart failure and NSAID use — GPhC CRA MCQ
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Correct answer: B — Avoid ibuprofen and advise medical review because NSAIDs can worsen heart failure
NSAIDs can cause sodium and water retention, reduce renal perfusion and worsen heart failure. The patient's worsening ankle swelling increases concern that their condition may be unstable. A non-NSAID analgesic approach and medical review are safer.
Reference: BNF; NICE CKS