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Oral thrush inhaled steroid — GPhC CRA MCQ

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HardInfectionsOral thrush inhaled steroidGPhC CRA

A patient using high-dose fluticasone via an Accuhaler dry-powder inhaler has symptomatic oral candidiasis but stable asthma. Which plan best addresses the adverse effect without destabilising asthma control?

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Correct answer: DTreat with a topical antifungal while continuing fluticasone; rinse after use and review technique and dose

The fluticasone SmPC permits topical antifungal treatment while fluticasone continues. The patient should rinse and gargle after each dose and have technique and the need for the high dose reviewed. An Accuhaler is a dry-powder device and cannot take a spacer. Abruptly removing anti-inflammatory treatment risks loss of control, while merely changing corticosteroid or using routine systemic prophylaxis does not correct the present infection and deposition problem.

Reference: Flixotide Accuhaler Summary of Product Characteristics: https://www.medicines.org.uk/emc/product/846/smpc