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Carbimazole sore throat warning — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsCarbimazole sore throat warningGPhC CRA

A patient taking carbimazole for Graves' disease asks to buy lozenges for a sore throat and fever. He started carbimazole 6 weeks ago. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Urgent FBC before further carbimazole

Carbimazole can cause agranulocytosis, especially early in treatment. Sore throat, fever or mouth ulcers should prompt urgent medical advice and blood count assessment. Symptomatic treatment alone may mask a serious adverse reaction. The patient should be told how to seek urgent help and the prescriber should be informed.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment