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Metoclopramide duration and EPS risk — GPhC CRA MCQ

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HardGI TherapeuticsMetoclopramide duration and EPS riskGPhC CRA

A young woman has been prescribed metoclopramide 10 mg three times daily for 4 weeks for nausea. She has no specialist review planned. What is the most appropriate alternative?

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Correct answer: B — Query the duration because metoclopramide use should be short term due to neurological adverse-effect risk

Metoclopramide can cause extrapyramidal adverse effects, and risk is relevant in younger patients. Treatment duration should usually be short and within recommended limits unless specialist justification exists. The pharmacist should query an extended 4-week course. Combining dopamine antagonists may increase adverse effects.

Reference: BNF; MHRA Drug Safety Update