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Corticosteroid infection risk — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyCorticosteroid infection riskGPhC CRA

A patient taking prednisolone 40 mg daily for 3 weeks reports exposure to chickenpox and has no history of previous infection or vaccination. What is the most appropriate action?

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Correct answer: DAdvise urgent medical advice because varicella exposure can be serious during systemic steroid therapy

Systemic corticosteroids can increase risk from infections such as varicella, depending on dose, duration and immunity. Significant exposure in a non-immune patient requires urgent advice because prophylaxis may be time-sensitive. Abrupt steroid cessation may be harmful. The pharmacist should escalate promptly.

Reference: BNF; NICE CKS