A woman of childbearing potential starting bosentan uses an etonogestrel implant as her only contraceptive method. Baseline pregnancy and liver tests

Question

A woman of childbearing potential starting bosentan uses an etonogestrel implant as her only contraceptive method. Baseline pregnancy and liver tests are normal. What safeguard is required?

Accepted Answer

Add an alternative or additional reliable contraceptive method, arrange monthly pregnancy tests and monthly liver enzymes

Answer

Stop all contraception because pregnancy is safe once pulmonary hypertension treatment begins

Answer

Only quarterly liver tests are needed once baseline results are normal

Answer

Replace monthly pregnancy testing with a single test three months after starting

Answer

The implant alone is sufficient because bosentan inhibits rather than induces steroid metabolism

Statin in active liver disease — GPhC CRA MCQ

A woman of childbearing potential starting bosentan uses an etonogestrel implant as her only contraceptive method. Baseline pregnancy and liver tests are normal. What safeguard is required?