Methotrexate patient-held record — GPhC CRA MCQ
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Correct answer: C — Clarify the weekly dosing day before supply and reinforce monitoring and toxicity advice
Methotrexate weekly dosing errors can be fatal, so the dosing day should be clear before supply. The pharmacist should reinforce the monitoring schedule, folic acid instructions and warning symptoms such as mouth ulcers or sore throat. Patient-held records can support safe use. 'As directed' without counselling is unsafe where the patient is uncertain.
Reference: BNF; MHRA; NPSA legacy guidance