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Controlled-release morphine counselling — GPhC CRA MCQ

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ModerateCNS TherapeuticsControlled-release morphine counsellingGPhC CRA

A patient collecting modified-release morphine tablets says she struggles to swallow large tablets and asks whether she can crush them in yoghurt. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Advise not to crush the tablets and contact the prescriber about a suitable formulation

Crushing modified-release morphine can destroy the release characteristics and may cause dose dumping with serious toxicity. The correct approach is to contact the prescriber or consider an appropriate alternative formulation. Immediate-release substitution requires a prescribed regimen and dose conversion. The patient should receive clear counselling on safe administration.

Reference: BNF; MEP