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DOAC renal dose review — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentDOAC renal dose reviewGPhC CRA

A patient taking rivaroxaban for atrial fibrillation has an eGFR of 24 mL/min/1.73 m2 on new blood tests. The repeat prescription remains unchanged. What is the most appropriate action?

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Correct answer: B — Contact the prescriber to review anticoagulant suitability and dose before supply

Renal function is important for DOAC dosing and suitability. An eGFR of 24 mL/min/1.73 m2 requires prompt prescriber review to balance stroke and bleeding risk. Pharmacists should not independently change to alternate-day dosing or substitute aspirin. Abrupt discontinuation may expose the patient to thromboembolic risk.

Reference: BNF; NICE CKS