skip to main content

Beta-blocker in Raynaud's — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCardiovascular TherapeuticsBeta-blocker in Raynaud'sGPhC CRA

A 48-year-old woman with Raynaud's phenomenon presents a prescription for propranolol 40 mg three times daily for newly diagnosed essential tremor. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Contact the prescriber as beta-blockers can worsen Raynaud's phenomenon

Non-selective beta-blockers such as propranolol block beta-2 receptors in peripheral blood vessels, causing unopposed alpha-mediated vasoconstriction. This can significantly worsen Raynaud's phenomenon. The prescriber should be contacted to discuss alternative treatments for essential tremor such as primidone. Even cardioselective beta-blockers should be used with caution in Raynaud's, as selectivity is dose-dependent.

Reference: BNF Propranolol; NICE CKS Essential Tremor